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[Stem Cell Reviews and Reports] 3D Microfabricated Scaffolds and Microfluidic Devices for Ocular Sur


Abstract:

In recent years, there has been increased research interest in generating corneal substitutes, either for use in the clinic or as in vitro corneal models. The advancement of 3D microfabrication technologies has allowed the reconstruction of the native microarchitecture that controls epithelial cell adhesion, migration and differentiation. In addition, such technology has allowed the inclusion of a dynamic fluid flow that better mimics the physiology of the native cornea. We review the latest innovative products in development in this field, from 3D microfabricated hydrogels to microfluidic devices.

Elisabetta PrinaPritesh MistryLaura E. SidneyJing YangRicky D. WildmanMarina BertolinClaudia BredaBarbara FerrariVanessa BarbaroAndrew HopkinsonHarminder S. DuaStefano FerrariEmail authorFelicity R. A. J. Rose First Online: 01 June 2017 DOI: 10.1007/s12015-017-9740-6 Cite this article as: Prina, E., Mistry, P., Sidney, L.E. et al. Stem Cell Rev and Rep (2017). doi:10.1007/s12015-017-9740-6

Link: https://link.springer.com/article/10.1007/s12015-017-9740-6

#06052017 #review #labonachip #Biologicalapplication

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