[Journal of Micromechanics and Microengineering] 3D printed micro/nanofluidic preconcentrator for ch
In this paper, we introduce a novel and simple method to fabricate a preconcentrator based on the ion concentration polarization phenomenon (ICP). Using a three-dimensional printed layer, the microchannels could be easily integrated with an ion exchange membrane which plays the role of the nanoporous junction needed for ICP. To demonstrate the preconcentration ability of the devices, we conducted experiments with negatively charged fluorescein sodium and positively charged rhodamine 6G. As a result, the negatively charged sample could be preconcentrated more than 18 fold by using a cation exchange membrane. The positively charged sample could be preconcentrated more than 40 fold by using an anion exchange membrane. This preconcentrator with a simple fabrication process could be implemented in various microfluidic systems for biochemical assays.
Hailong Pi1,2, Jianhua Tong1, Chao Bian1 and Shanhong Xia1 Published 29 March 2017 • © 2017 IOP Publishing Ltd Journal of Micromechanics and Microengineering, Volume 27, Number 5