[Talanta] Solid-phase extraction microfluidic devices for matrix removal in trace element assay of a
Advances in sample nebulization and injection technology have significantly reduced the volume of solution required for trace impurity analysis in plutonium and uranium materials. Correspondingly, we have designed and tested a novel chip-based microfluidic platform, containing a 100-µL or 20-µL solid-phase microextraction column, packed by centrifugation, which supports nuclear material mass and solution volume reductions of 90% or more compared to standard methods. Quantitative recovery of 28 trace elements in uranium was demonstrated using a UTEVA chromatographic resin column, and trace element recovery from thorium (a surrogate for plutonium) was similarly demonstrated using anion exchange resin AG MP-1. Of nine materials tested, compatibility of polyvinyl chloride (PVC), polypropylene (PP), and polytetrafluoroethylene (PTFE) chips with the strong nitric acid media was highest. The microcolumns can be incorporated into a variety of devices and systems, and can be loaded with other solid-phase resins for trace element assay in high-purity metals.
Jun Gao, Benjamin T. Manard, Alonso Castro, Dennis P. Montoya, Ning Xu , Rebecca M. Chamberlin, Los Alamos National Laboratory, P.O. Box 1663, MS G740, Los Alamos, NM 87545, USA Received 3 January 2017, Revised 25 January 2017, Accepted 27 January 2017, Available online 2 February 2017