[Patent] Pressure Manifold and Culture Module
A perfusion manifold assembly is described that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body.
Document Type and Number: United States Patent Application 20170058248
Kind Code: A1
Inventors: Hinojosa, Christopher David (Cambridge, MA, US) Thompson, Guy Robert (Watertown, MA, US) Gomes, Joshua (Somerville, MA, US) Freake, Jacob (Somerville, MA, US) Sabin, Doug (Woburn, MA, US)