[Analytical Methods] Microfluidic Biochip and Integrated Diffractive Optics for Bacteria Growth Cont
We present a simple and inexpensive method for enabling bacterial cell capture in a 2D array of traps, such that their growth can be monitored under controlled dynamic environments through diffraction optics integrated into a microfluidic chip. As an example, we demonstrate the feasibility for E. coli capture and expansion within the monolayer trap; the resulting increase in diffraction signal is consistent with the cells’ exponential growth rate.
Cynthia Goh and Vitali Borisenko Anal. Methods, 2017, Accepted Manuscript DOI: 10.1039/C6AY03311C Received 08 Dec 2016, Accepted 20 Mar 2017 First published online 20 Mar 2017