[Lab on a chip] Device and programming abstractions for spatiotemporal control of active micro-parti
We present a hardware setup and a set of executable commands for spatiotemporal programming and interactive control of a swarm of self-propelled microscopic agents inside a microfluidic chip. In particular, local and global spatiotemporal light stimuli are used to direct the motion of ensembles of Euglena gracilis, a unicellular phototactic organism. We develop three levels of programming abstractions (stimulus space, swarm space, and system space) to create a scripting language for directing swarms. We then implement a multi-level proof-of-concept biotic game using these commands to demonstrate their utility. These device and programming concepts will enhance our capabilities for manipulating natural and synthetic swarms, with future applications for on-chip processing, diagnostics, education, and research on collective behaviors.
Amy T. Lam,a Karina G. Samuel-Gama,a Jonathan Griffin,a Matthew Loeun,a Lukas C. Gerber,a Zahid Hossain,a Nate J. Cira,a Seung Ah Leea and Ingmar H. Riedel-Kruse*a Show Affiliations Lab Chip, 2017, Advance Article DOI: 10.1039/C7LC00131B