[Annual Review of Biomedical Engineering - Highly Cited] Physics and Applications of Microfluidics i
Fluid flow at the microscale exhibits unique phenomena that can be leveraged to fabricate devices and components capable of performing functions useful for biological studies. The physics of importance to microfluidics are reviewed. Common methods of fabricating microfluidic devices and systems are described. Components, including valves, mixers, and pumps, capable of controlling fluid flow by utilizing the physics of the microscale are presented. Techniques for sensing flow characteristics are described and examples of devices and systems that perform bioanalysis are presented. The focus of this review is microscale phenomena and the use of the physics of the scale to create devices and systems that provide functionality useful to the life sciences.
David J. Beebe, Glennys A. Mensing, and Glenn M. Walker
Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53706; e-mail: email@example.com
Annual Review of Biomedical Engineering
Vol. 4:261-286 (Volume publication date August 2002) DOI: 10.1146/annurev.bioeng.4.112601.125916