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[Conference]On-chip internalization process of an intracellular nanobot into a single cell


Abstract:

This paper reports on-chip internalization of an intracellular nanobot into a single cell with a microfluidic device. The nanobot was made of a Ni sputtered carbon naocoil and driven by a rotating magnetic field. Here, we fabricated the microfluidic device to capture a single cell by a soft lithography technique and demonstrated on-chip internalization of the nanobot. As a result, a single cell was captured in the microfluidic device and the nanobot was successfully internalized into the trapped cell. Additionally the nanobot could be driven at a speed of 0.35 μm/s inside the cell. This result indicates the potential of the nanobot which can move to any positions inside a single cell for intracellular stimulation.

Published in: Micro Electro Mechanical Systems (MEMS), 2017 IEEE 30th International Conference on

Date of Conference: 22-26 Jan. 2017

Date Added to IEEE Xplore: 28 February 2017

DOI: 10.1109/MEMSYS.2017.7863473

K. Ogawa

Osaka University, Suita, Japan

K. Uesugi

Osaka University, Suita, Japan

K. Morishima

Osaka University, Suita, Japan

Link: http://ieeexplore.ieee.org/abstract/document/7863473/

#singlecell #nanobot #MEMS #Biologicalapplication

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