Abstract:

“Cell Pinball” is a phenomenon whereby rotating red blood cells (RBCs) move like pinballs inside a microfluidic channel where the cell inertia is negligible. The goal of this paper is to discuss the location of the actual rotational axis through the careful comparison between the contour and contact shapes of a moving RBC. By switching the reflection interference contrast (RIC) and the phase contrast (PhC) microscopes with the mean cycle time of 0.440 s, we found that the difference between the trajectories of each centroid of the visualized RBC by RIC and PhC is less than 0.8 μm.

Conference: Micro Electro Mechanical Systems (MEMS), 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS)

Date of Conference: 22-26 Jan. 2017

Date Added to IEEE Xplore: 28 February 2017

DOI: 10.1109/MEMSYS.2017.7863667

Ryo Murakami

Department of Mechanical Engineering, Osaka University, Osaka, Japan

Akihisa Yamamoto

Institute for Integrated Cell-Material Science (WPI iCeMS), Kyoto University, Kyoto, Japan

Hiroaki Ito

Department of Mechanical Engineering, Osaka University, Osaka, Japan

Chia-Hung Dylan Tsai

Department of Mechanical Engineering, Osaka University, Osaka, Japan

Mitsuhiro Horade

Department of Mechanical Engineering, Osaka University, Osaka, Japan

Motomu Tanaka

Institute of Physical Chemistry, University of Heidelberg, Heidelberg, Germany

Makoto Kaneko

Department of Mechanical Engineering, Osaka University, Osaka, Japan

Link: http://ieeexplore.ieee.org/abstract/document/7863667/

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