- Microfluidics News Admin
[Conference]Observation of cell pinball through high speed switching between reflection interference
Abstract:
“Cell Pinball” is a phenomenon whereby rotating red blood cells (RBCs) move like pinballs inside a microfluidic channel where the cell inertia is negligible. The goal of this paper is to discuss the location of the actual rotational axis through the careful comparison between the contour and contact shapes of a moving RBC. By switching the reflection interference contrast (RIC) and the phase contrast (PhC) microscopes with the mean cycle time of 0.440 s, we found that the difference between the trajectories of each centroid of the visualized RBC by RIC and PhC is less than 0.8 μm.
Conference: Micro Electro Mechanical Systems (MEMS), 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS)
Date of Conference: 22-26 Jan. 2017
Date Added to IEEE Xplore: 28 February 2017
DOI: 10.1109/MEMSYS.2017.7863667
Ryo Murakami
Department of Mechanical Engineering, Osaka University, Osaka, Japan
Akihisa Yamamoto
Institute for Integrated Cell-Material Science (WPI iCeMS), Kyoto University, Kyoto, Japan
Hiroaki Ito
Department of Mechanical Engineering, Osaka University, Osaka, Japan
Chia-Hung Dylan Tsai
Department of Mechanical Engineering, Osaka University, Osaka, Japan
Mitsuhiro Horade
Department of Mechanical Engineering, Osaka University, Osaka, Japan
Motomu Tanaka
Institute of Physical Chemistry, University of Heidelberg, Heidelberg, Germany
Makoto Kaneko
Department of Mechanical Engineering, Osaka University, Osaka, Japan