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[Conference]Code-division multiplexed resistive pulse sensor networks for spatio-temporal detection


Abstract:

Spatial separation of suspended particles based on contrast in their physical or chemical properties forms the basis of various biological assays performed on lab-on-a-chip devices. To electronically acquire this information, we have recently introduced a microfluidic sensing platform, called Microfluidic CODES, which combines the resistive pulse sensing with the code division multiple access in multiplexing a network of integrated electrical sensors. In this paper, we enhance the multiplexing capacity of the Microfluidic CODES by employing sensors that generate non-orthogonal code waveforms and a new decoding algorithm that combines machine learning techniques with minimum mean-squared error estimation. As a proof of principle, we fabricated a microfluidic device with a network of 10 code-multiplexed sensors and characterized it using cells suspended in phosphate buffer saline solution.

Published in: Micro Electro Mechanical Systems (MEMS), 2017 IEEE 30th International Conference on

Date of Conference: 22-26 Jan. 2017

Date Added to IEEE Xplore: 28 February 2017

DOI: 10.1109/MEMSYS.2017.7863416

Ningquan Wang

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, USA

Ruxiu Liu

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, USA

Roozbeh Khodambashi

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, USA

Norh Asmare

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, USA

A. Fatih Sarioglu

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, USA

Link: http://ieeexplore.ieee.org/abstract/document/7863416/

#MEMS #sensor #particledetection

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