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[Conference]An artificial cilia based micromixer for superior zebrafish sperm activation


Abstract:

The objective of this study is to propose an artificial cilia based microfluidic device for efficient activation of zebrafish sperm by controlling the hydro-dynamics induced on the zebrafish sperm from the artificial cilia beating. The magnitude of fluid shear which has significant effect on the success of sperm activation was precisely controlled through this proposed device. A superior sperm activation of an absolute value of 70% with an average value of 65 % was achieved with a statistical significance (p-value < 0.05). The present design will advance the practice of the sperm activation significantly through the microfluidic platform.

Published in: Micro Electro Mechanical Systems (MEMS), 2017 IEEE 30th International Conference on

Date of Conference: 22-26 Jan. 2017

Date Added to IEEE Xplore: 28 February 2017

DOI: 10.1109/MEMSYS.2017.7863641

Chia-Yuan Chen

Department of Mechanical Engineering, National Cheng Kung University, Tainan 701, Taiwan

Pin-Yi Huang

Department of Mechanical Engineering, National Cheng Kung University, Tainan 701, Taiwan

Bivas Panigrahi

Department of Mechanical Engineering, National Cheng Kung University, Tainan 701, Taiwan

Link: http://ieeexplore.ieee.org/abstract/document/7863641/

#MEMS #microchannels #Biologicalapplication

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