Abstract:

This paper reports a novel bioMEMS device that integrates mechanical constriction for single cell trap in the channels, which are enclosed by thick (or 3D) C-PDMS (carbon-black-PDMS) electrodes and bottom planar transparent electrode for dielectrophoretic (DEP) cell manipulation. Leveraging hydrodynamics and dieletrophoresis, this simple biomedical microsystem enables more efficient loading of one single cell in place and controllable 3D cell rotation than before.

Published in: Micro Electro Mechanical Systems (MEMS), 2017 IEEE 30th International Conference on MEMS

Date of Conference: 22-26 Jan. 2017

Date Added to IEEE Xplore: 28 February 2017

DOI: 10.1109/MEMSYS.2017.7863450

Liang Huang

State Key Laboratory of Precision Measurement Technology and Instrument, Department of Precision Instrument, Tsinghua University, Beijing, China

Peng Zhao

State Key Laboratory of Precision Measurement Technology and Instrument, Department of Precision Instrument, Tsinghua University, Beijing, China

Shengtai Bian

Department of Biomedical Engineering, Tsinghua University, Beijing, China

Guanya Shi

Department of Automotive Engineering, Tsinghua University, Beijing, China

Peng Liu

Department of Biomedical Engineering, Tsinghua University, Beijing, China

Song Zong

State Key Laboratory of Precision Measurement Technology and Instrument, Department of Precision Instrument, Tsinghua University, Beijing, China

Wenhui Wang

State Key Laboratory of Precision Measurement Technology and Instrument, Department of Precision Instrument, Tsinghua University, Beijing, China

Link: http://ieeexplore.ieee.org/abstract/document/7863450/

#MEMS #singlecell #dielectrophoresis #electrode #biomems