Microfluidics News AdminSep 12, 20172 min[Materials Science and Engineering: C] Characterization and degradation study of chitosan-siloxane hAbstract: Chitosan microspheres can address challenges associated with poor bioavailability or unsustained drug release when used as drug delivery systems thanks to their mucoadhesiveness, which allows the drug dosage to be retained in the gastrointestinal track for extended periods. Chitosan-3-glycidoxypropyltrimethoxysilane-β-glycerophosphate (chitosan-GPTMS-β-GP) hybrid microspheres were synthetized through sol-gel processing using a microfluidic approach. Microspheres wit
Microfluidics News AdminApr 18, 20172 min[ACS Appl. Mater. Interfaces] Cell Isolation and Recovery Using Hollow Glass Microspheres Coated witAbstract: Established cell isolation and purification techniques such as FACS, isolation through magnetic micro/nano-particles and recovery via microfluidic devices have limited application as disposable technologies appropriate for point-of-care use in remote areas where lab equipment as well as electrical, magnetic, and optical sources are restricted. We report a simple yet effective method for cell isolation and recovery that requires neither specialized lab equipment nor
Microfluidics News AdminApr 4, 20172 min[Thesis] PolyHIPE Microspheres for Injectable Bone Tissue Engineering ApplicationsAbstract: Injectable microsphere-based delivery systems have great potential in tissue engineering, since they remove the need for open surgery. Current bone filler systems for non-load bearing applications do not fully resorb and only allow regrowth of bone at the implant interface. Within this thesis, a tissue engineered injectable bone filler was developed and optimised. This was in the form of polymeric microspheres that support human embryonic stem cell-derived mesenchym
